A Les Paul feels different from a Strat in several ways.
Body shape
The Les Paul has a slab body shape, while the Strat has a contoured body shape. This means that the Les Paul is more square and boxy, while the Strat is more rounded and comfortable to hold.
Neck profile
The Les Paul typically has a thicker neck profile than the Strat. This can make it more difficult to play for people with smaller hands, but it can also provide more stability and support for people with larger hands.
Weight
Les Pauls are typically heavier than Strats. This can make them more uncomfortable to play for long periods of time, but it can also contribute to their fuller, warmer sound.
Sound
Les Pauls are known for their warm, full sound. This is due in part to their thicker neck profile, heavier body, and humbucking pickups. Strats are known for their bright, clear sound. This is due in part to their thinner neck profile, lighter body, and single-coil pickups.
Overall feel
Les Pauls feel more solid and substantial than Strats. They are also heavier and have a thicker neck profile. Strats feel more lightweight and agile. They have a thinner neck profile and a more contoured body shape.
Which guitar is right for you?
Whether you prefer a Les Paul or a Strat is a matter of personal preference. There is no right or wrong answer. It depends on what you are looking for in a guitar and the type of music you want to play.
If you are looking for a guitar with a warm, full sound and a solid build, then a Les Paul is a good choice. If you are looking for a guitar with a bright, clear sound and a comfortable body shape, then a Strat is a good choice.
Ultimately, the best way to decide which guitar is right for you is to try them both out and see which one you prefer. There is no substitute for playing a guitar in person and getting a feel for it yourself.